Over 95% of individuals with Down syndrome in the U.S. do not have access to a Down syndrome specialty clinic. Researchers at Massachusetts General Hospital and Harvard Medical School have now created “Down Syndrome Clinic to You” (DSC2U) as a way to bring the latest advances in health and wellness for people with Down syndrome directly to caregivers’ home computers. With DSC2U (dsc2u.org), caregivers complete an online intake form, where they identify current concerns about their son or daughter with Down syndrome. Their responses generate two personalized documents: a plan for caregivers and another one for the primary care providers of their sons/daughters. Funded by a national PCORI grant, Dr. Skotko will review the efficacy and satisfaction results of more than 200 English- and Spanish-speaking families who have already used DSC2U. This workshop will include a demonstration of DSC2U so that all families feel empowered to begin using in their own homes.